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dr Paolo Macchiarini is a former surgeon who attracted public attention from his humble beginnings in Italy. He was consered a highly qualified surgeon and also conducted research in the field of regenerative medicine.
However, his life took a devastating turn when his research fraud and manipulative behavior became public knowledge. He is also defamed for unlicensed synthetic surgeries, even resulting in the death of many patients.
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Surname
dr Paolo Macchiarini
birthday
Aug. 22, 1958
Age
62
gender
Masculine
Height
5 feet 8 inches
nationality
Italian
profession
The surgeon
Married single
Married
education
University of Pisa
@paolomacchiarin
10 Facts on Dr. Paolo Macchiarini
dr Paolo Macchiarini was born on August 22, 1958 in Sweden to an Italian family. Despite the difference in his place of birth, he is known to be Italian due to his nationality. Despite having a wife and family, Paolo has been in a public affair with internet star Benita Alexandra. For data protection reasons, the entity of his wife is not disclosed on the Internet. dr Paolo is 62 years old in 2020 and has been working in the medical field for more than a decade. However, due to several large fines and lawsuits in the past, it was very difficult to calculate his total net worth. A detailed biography of Dr. Paolo can be found on an official Wikipedia page. According to Vanity Fair, Dr. Paolo is also accused of allegedly publishing fake information on his academic resume. He remains low key at the moment and there is no content about him that we can update. He graduated in Medical Sciences from the University of Pisa. He also received his Masters in Surgery from the University in 1991.Dr. Paolo reportedly received his organ and tissue transplant license from the University of Alabama. During his time in Europe, Paolo worked as a thoracic and vascular surgeon at the Clinic de Barcelona. He began synthetic surgery while he was at Heehaus Hospital, leading to his inevitable downfall. dr Paolo has a dead Twitter account @paolomacchiarin. He has not been active since 2019.
What is Benita Alexander doing now?
Where is Benita Alexander now? Since her romance with Paolo imploded in 2015, the brunette beauty has continued working on documentaries and docuseries‘.
Who is Paolo Macchiarini real wife?
What happened to Paolo the surgeon?
Paolo Macchiarini, once seen as a pioneering transplant surgeon, was cleared of two charges of assault. Three patients treated in Sweden died. Prosecutors had recommended Macchiarini serve five years in jail but the district court ruled that he had not intended to cause the patients harm.
Is Paolo Macchiarini a real surgeon?
Paolo Macchiarini (born 22 August 1958) is a Swiss-born Italian thoracic surgeon and former regenerative medicine researcher who became known for research fraud and manipulative behavior.
How did Benita meet Paolo?
Benita Alexander and Paolo Macchiarini fall in love. Alexander, an award-winning documentary TV producer, met Macchiarini in 2013 while working on a story about the surgeon’s pioneering work transplanting synthetic tracheas, or windpipes.
Who is Benita and Paolo?
Before the Tinder Swindler, there was celebrity surgeon Dr Paolo Macchiarini. You may already be familiar with him as the calculating ‘Miracle Man’ — he featured on Season 3 of the Wondery podcast Dr. Death — but Benita Alexander knew him as her charming friend and confidante-turned-fiancé.
Who discovered trachea?
Vesalius in 1543 reported the first tracheal intubation in an animal. Trousseau reported 200 patients suffering from diphtheria who were saved by tracheostomy.
Where can i stream he lied about everything?
Streaming on Roku. He Lied About Everything, a documentary series is available to stream now. Watch it on Philo on your Roku device.
Can you have a trachea transplant?
A team of Mount Sinai surgeons has performed the world’s first human tracheal transplant—an achievement that has the potential to save the lives of thousands of patients around the world who have tracheal birth defects, untreatable airway diseases, burns, tumors, or severe tracheal damage from intubation, including …
Is there an artificial trachea?
A 36-year-old man returned home this week after receiving the world’s first “synthetic” trachea in an operation at the Karolinska University Hospital in Stockholm, Sweden. Made of a bendy polymeric nanocomposite material, the trachea could be the first of many “off-the-shelf” organs for transplant.
What is artificial trachea?
Macchiarini made headlines around the world after claiming a major breakthrough for patients with failing windpipes, by “seeding” an artificial scaffold with a patient’s own stem cells, to generate a functioning trachea.
Who is the super surgeon?
A little over two years ago, thoracic surgeon Paolo Macchiarini soared to the top and then sunk to the bottom within days. First, his work implanting artificial tracheas hit the front page of the New York Times. Days later he was placed on house arrest for accusations of fraud and extortion.
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Paolo Macchiarini – Wikipedia
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Bio, Net Worth, Age, Family, Affairs, Married, Wife, Now, Salary, Height, Parents, Nationality, Facts, Wiki, Career, Education
A Swiss-born Italian thoracic surgeon is named after Paolo Macchiarini. He is also a former regenerative medicine researcher. He is known for his research fraud and manipulative behavior. He was considered a pioneer in the field of regenerative medicine, using both biological and synthetic scaffolds with the patient’s own stem cells as tracheal transplantation, and was a visiting researcher on a temporary contract at Karolinska Institutet in Sweden from 2010. He was charged with research misconduct and unethically performing experimental surgery, even on relatively healthy patients. Seven of the eight patients who received his artificial trachea transplants have died. When he was working for Karolinska Institute his contract was terminated and he then started working at Kazan Federal University (Volga region) in Russia until the university ended his project in April 2017 and effectively fired him. As of 2020, eight of his research papers have been withdrawn and two received a concern.
9 things you didn’t know about Benita Alexander-Jeune
Famous for
As a Swiss-born Italian transplant surgeon.
For being credited with medical miracles, including the world’s first synthetic organ transplant, in which a windpipe or trachea was made out of plastic and then coated with a patient’s own stem cells.
Source: @community.babycenter.com
What is the birthplace of Paolo Macchiarini?
On August 22, 1958 Paolo Macchiarini was born in Basel, Switzerland (place of birth). He holds Swiss citizenship and his ethnicity is Swiss White. Hence his race is White. He was born to Italian parents. He spent his childhood in Basel. As of 2020, he celebrated his 62nd birthday. Leo is his zodiac sign and his religion is Christian. Details about her father and mother’s names and siblings have not yet been released. Regarding his educational background, Paolo received his medical degree (equivalent to MD) in 1986 from the Faculty of Medicine, University of Pisa, Italy. In 1991 he received a Master of Surgery and from that year became an assistant professor from 1990 to 1992. In addition, in 1989 he took a course in statistics in clinical research at the University of Alabama at Birmingham. He also earned diplomas; Masters in organ and tissue transplantation from 1994 and doctorate in the same from 1997 at the University of Franche-Comte. From 1999 to 2004 he was also head of the department for thoracic and vascular surgery at the Heidehaus Hospital in Hanover. From 2006 to 2009 he was an investigator at the Institut d’Investigacions Biomédiques-Instituto de Investigaciones Biomédicas in Barcelona. He was also an employee at the Hospital Clínic de Barcelona. From 2009 to 2014 he was a visiting professor at University College London. In 2010 he was a consultant and project manager at the Careggi University Hospital and in the same year he was appointed visiting professor at the Karolinska Institute, and he also worked part-time as a surgeon at the affiliated university hospital. Karolinska later terminated the contract by releasing the incomplete review of his resume in February 2016. He later performed a tracheal transplant in Russia, which led to an appointment to Kuban State Medical University, funded by the university and the Russian government. He transferred to Kazan Federal University in 2016, but in April 2017 the university ended his research project.
How was Paolo Macchiarini’s career?
Notable tracheal surgeries
In June 2008, Paolo performed a transplant of a donated trachea seeded with stem cells from recipient Claudia Castillo. The tissue was used to replace her left bronchus, which had been damaged by tuberculosis and caused her left lung to collapse. The trachea was successfully transplanted by a team led by Macchiarini at the Hospital Clinic in Barcelona.
After this, he next participated in a transplant performed by Great Ormond Street surgeons on a 10-year-old Irish boy named Ciaran Finn-Lynch, performed in a manner similar to Castillo’s.
He also performed a transplant on Kaziah Shorten who was diagnosed with tracheal cancer in 2010 but the transplant failed the next year and later in 2011 was at University College Hospital London.
He also implanted a donated trachea in a woman in Russia in 2010 in collaboration with Russian surgeon Vladimir Parshin.
Next he came to the man Andemariam Teklesenbet Beyene, who was diagnosed with cancer. The operation took place in June 2011 and received extensive media coverage, including a cover story in The New York Times. Andemariam died in January 2013 after the implant failed. The autopsy revealed he had chronic pneumonia, a clot in his lungs, and a loosened windpipe.
Christopher Lyles asked Paolo to do the same thing Beyene and Macchiarini asked for by making a fully synthetic trachea using Lyles stem cells and implanting it in Karolinska in November 2011. In 2012, Lyles died suddenly.
Next, he implanted a fully synthetic inoculated trachea in Yulia Tuulik at the Kuban State Medical University from June 2012. The trachea later collapsed and was replaced; she died in 2014.
He implanted a fully synthetic vaccinated trachea in Alexander Zozulya at the Kuban State University in June 2012, but the patient died in February 2014.
Yesim Cetir, a Turkish woman, died in March 2017 after being treated by Paolo Macchiarini.
He then implanted a fully synthetic seeded trachea in Hannah Warren in April 2013. The surgery was performed in the US at OSF Saint Francis Medical Center in Peoria, Illinois. She later died on July 6, 2013 as a result of the second operation.
The next patient, Sadiq Kanaan, received a fully synthetic seeded tracheal implant from Macchiarini at Kuban State University in August 2013, but died that same year.
He implanted a fully synthetic seeded trachea in Dmitry Onogda at Kuban State University in June 2014, but the implant failed and was replaced. As of 2017, Dmitri was still alive.
Now he was planning another first: an artificial trachea transplant for a child, a two-year-old Korean-Canadian girl named Hannah Warren, who had spent her entire life in a Seoul hospital. Hannah Warren died of postoperative complications less than three months after the transplant.
Where exactly Paolo Macchiarini is now is unclear.
Source: @bbc.com
Paolo Macchiarini allegations
Paolo Macchiarini was arrested in Italy in 2012 and charged with asking patients at Careggi University Hospital for money to speed up their procedures. The charges were later dismissed in May 2015.
He was next accused by four former colleagues and co-authors of making false claims in his research. It was in 2014.
Then Swedish Television’s investigative television program Document inifran, which began broadcasting a three-part series entitled Experiments examining Macchiarini’s work. The documentary featured Macchiarini continuing operations with the new method even after they promised little or nothing, and exaggerated the health of his patients in articles as they died one by one. Allegations were also made that the medical condition of the patients both before and after the surgeries. But Paolo said the synthetic trachea had been tested on animals before being used on humans, which could not be verified.
The BBC later aired a three-part “Storyville” documentary called Fatal Experiments: The Downfall of a Supersurgeon, directed by Bosse Lindquist and based on previous Swedish programs on Macchiarini. It was broadcast in October 2016.
court proceedings
Swedish police launched an investigation into whether Paolo may have been killed through negligence. It was June 2016.
Police prosecutors announced in October 2017 that all criminal charges against Paolo had been dropped.
Later in 2019, an Italian court sentenced him to 16 months in prison for abuse of office and forgery.
Mikael Bjork, Director of Public Prosecutions in Sweden, charged an unnamed surgeon with aggravated assault on September 19, 2020. Swedish news agency TT said the surgeon accused was Dr. Paolo Macchiarini. Björk said he resumed the investigation in December 2018 and received new written evidence and interviewed people in five different countries. Björk said the victims had suffered “severe physical injuries and great suffering” from the operations performed on them and he “made the assessment that the three operations should therefore be considered serious bodily harm”.
Who is Paolo Macchiarini married to?
Paolo Macchiarini is a married man. In 1986 he married his beautiful wife Emanuela Pecchia. After the death of his father, he started his own family. The couple; Paolo and Emanuela are also proud parents of two children (a daughter and a son). His sexual orientation is straight and he is not gay.
Relationship with Benita Alexander
Paolo and Benita Alexander first met at the bar of Boston’s Mandarin Oriental hotel. It was February 2013, just before Macchiarini would conduct his first interview with Meredith Vieira for a two-hour NBC special titled A Leap of Faith. Then, in the spring of 2013, Alexander and Macchiarini reunited for a period of weeks in Illinois – brought there by the NBC special. After that, they often met for quiet dinners. Later, their romantic moment started after they flew to Venice. He also bought her red roses and Venetian glass earrings and took her on a gondola ride under the Bridge of Sighs. After her time in Venice, she flew to Macchiarini in Stockholm two weeks later. “We always spent our nights together and were always romantic in one way or another,” she said. By the time Macchiarini and Alexander flew to Europe for another romantic getaway in October 2013, she had reconciled her personal and professional demeanor. “Paolo proposed to Benita on Christmas Day 2013,” Benita said. The duo has traveled to the Bahamas, Turkey, Mexico, Greece and Italy. They went shopping and ate their way through Michelin-star restaurants. He even took Alexander and her daughter to meet his mother at her home in Lucca. “She cooked homemade gnocchi,” Alexander recalls. Benita is currently working on documentaries and docuseries. She’s also worked to share her own story with the public, and she was the subject of the 2018 documentary He Lied About Everything. In The Con, she once again shares her perspective on what’s between her and her Happened to ex-fiancé. Hundreds of Benita Alexander’s friends and family had already bought their plane tickets to Italy to attend her extravagant wedding to be celebrated by the Pope when everything collapsed in a spate of deceit from her fiancé. None of the promises Alexander had made to her fiancé Paolo Macchiarini for their wedding day would come true. As Alexander began to unravel the web of lies Macchiarini had told her, she began to wonder if the world-renowned thoracic surgeon had misled people in his professional life.
Source: @nypost
Everything you need to know about Benita Alexander-Jeune
About the personal life of Benita Alexander, she is a married woman. Married to fellow reporter John Noel, she moved to New York City, where she joined NBC’s Dateline. With him she also has a daughter named Jessina. They later divorced in 2009.
What is Paolo Macchiarini Net Worth?
Paolo Macchiarini is a famous thoracic surgeon and former regenerative medicine researcher. As of 2021, Paolo Macchiarini’s net worth is estimated at $1.4 million from his occupation, according to sources. While his exact salary is yet to be determined, there is no doubt for his followers that he makes a good amount of money from his work. His main source of wealth comes from a surgeon’s career. He lives a cool lifestyle off his career earnings and is happy with what he’s getting today.
How tall is Paolo Macchiarini?
Paolo Macchiarini is a very handsome surgeon with a charming smile and a radiant face. At 62, he still looks very young. He has taken great care of his body through frequent exercises. His hair color is gray and he has a pair of brown eye color. His physique is average. He stands upright at the perfect height that matches his body weight. Reasons behind his amazing personality could be his roots. His other body measurements have not yet been released. Overall he has a healthy body.
Where Is Benita Alexander From ‘The Con’ Now She’s Sharing Her Story
While working on the story with Paolo, Benita fell in love with him. Over the course of two years, the couple became engaged and Paolo promised her a wedding, which was celebrated by none other than his patient, Pope Francis. The Obamas and the Clintons were invited to the wedding, and it became one of the hottest events on people’s social calendars — although it never happened.
In reality, Paolo had not worked with the Pope and was still married to his wife for 30 years.
Paolo Macchiarini
Swiss-born Italian doctor
Paolo Macchiarini (born August 22, 1958)[1]: 2 is a Swiss-born Italian thoracic surgeon and former regenerative medicine researcher who became known for research fraud and manipulative behavior.[2][3]
Macchiarini was previously credited with pioneering the use of both biological and synthetic scaffolds seeded with the patient’s own stem cells as tracheal grafts. Since 2010, Macchiarini has been a visiting professor and director with a fixed-term contract at Karolinska Institutet (KI) in Sweden.[4] Macchiarini has been accused of unethically performing experimental surgeries, even on relatively healthy patients, resulting in the deaths of seven of the eight patients who received one of his synthetic trachea transplants.[5] Articles in Vanity Fair and Aftonbladet also suggested that he forged some of his academic credentials on resumes.
Urban Lendahl [sv], the secretary of the Nobel Committee on Physiology or Medicine, resigned in February 2016 due to his involvement in recruiting Macchiarini to AI.[8] Shortly thereafter, Vice Chancellor Anders Hamsten [sv], who had acquitted Macchiarini of wrongdoing in 2015, also resigned.[9] KI ended his clinical relationship with Macchiarini in 2013 but allowed him to continue as a researcher; in February 2016, the university announced that it would not renew his research contract, which expired in November, and terminated the contract the following month.[10] After being fired from KI, Macchiarini worked at Kazan Federal University in Russia until that institution terminated his project in April 2017, effectively firing him.[11][12]
After a year-long medico-legal investigation, Swedish prosecutors announced in October 2017 that Macchiarini had acted negligently in four of the five cases investigated for using devices and procedures not supported by evidence, but that it could not be a proven criminal offense , because the patients could have died on any other given treatment.[13][14] Also in October, the Swedish Expert Group on Scientific Misconduct found evidence of research fraud by Macchiarini and his co-authors in six publications and called for their retraction.[15] As of 2020, eight of his research papers have been withdrawn by Macchiarini and two have raised concerns.[16]
Education and job[edit]
Paolo Macchiarini received his medical degree (equivalent to MD) from the Medical Faculty of the University of Pisa (UniPi) in 1986 and a Master of Surgery in 1991.[17] From 1990 to 1992 he was an assistant professor at UniPi.[17] He took a course in statistics in clinical research at the University of Alabama at Birmingham in 1989.[17] Macchiarini received diplomas – a Masters in Organ and Tissue Transplantation from 1994 and a PhD in the same from 1997 – from the University of Franche-Comté in France.[17] According to the Hanover Medical School, he was never employed there, but headed the department for thoracic and vascular surgery at the Heidehaus Hospital in Hanover from 1999 to 2004.[17] Macchiarini was a researcher at the Institut d’Investigacions Biomèdiques-Instituto de Investigaciones Biomédicas in Barcelona, Spain from 2006 to 2009; he was affiliated with the University of Barcelona but not an employee, and was apparently an employee of the Hospital Clínic de Barcelona at the time.[17] From 2009 to 2014 he held an honorary appointment as Visiting Professor at University College London.[17] From 2010 he was a consultant and project manager at the University Hospital Careggi (AOUC).[17]
Later in 2010, Macchiarini was appointed visiting professor at the Karolinska Institute (KI) in Stockholm and a part-time post as a surgeon at the affiliated university hospital.[17] In 2013, KI ended his clinical relationship with Macchiarini but allowed him to continue as a researcher; in February 2016, the university announced that it would not renew Macchiarini’s research contract, which expired in November, and terminated the contract the following month.[10][18] KI published the incomplete results of its review of Macchiarini’s CV in February 2016.[17]
Macchiarini established ties to Russia after giving a master class in 2010 at the invitation of politician Mikhail Batin; a few months later he performed a trachea transplant there, which was widely reported in the Russian media.[12] This led to Macchiarini’s 2011 appointment to the Kuban State Medical University, funded by the university and the Russian government,[12] along with an honorary doctorate.[17] In 2016 he transferred to Kazan Federal University and the scholarship dealt with him.[12] In April 2017, the University of Macchiarini ended the research project there.[12]
Notable tracheal surgeries[ edit ]
Claudia Castillo[edit]
In June 2008, Macchiarini performed a transplant of a donated trachea seeded with stem cells from recipient Claudia Castillo; the tissue was used to replace her left bronchus damaged by tuberculosis, and her left lung had collapsed.[19] The trachea was taken from a cadaver and stripped of its cells and seeded with cells from Castillo’s bone marrow. The bone marrow cells were cultured at the University of Bristol, the donor trachea was removed at the University of Padua, the removed trachea was seeded with the cultured cells at the University of Milan and the trachea was transplanted by a team led by Macchiarini at the hospital clinic in Barcelona. [19][22]
Ciaran Finn Lynch[edit]
In March 2010, Macchiarini attended a transplant performed by Great Ormond Street surgeons. Similar to Castillo on a ten-year-old Irish boy, Ciaran Finn-Lynch, at Great Ormond Street Hospital in London.[23] The boy was born with a 1mm diameter trachea, and attempts to dilate it had caused life-threatening complications.[23] In contrast to the Castillo procedure, in this case the exposed trachea was seeded with the boy’s stem cells just a few hours before the implantation.
Shorten Keziah [ edit ]
Keziah Shorten had tracheal cancer. In 2010, Macchiarini performed a transplant similar to the previous two; The transplant failed the next year and in 2011 an artificial trachea was implanted for palliative care at University College Hospital London, after which she was able to be discharged and return home with her family over Christmas before succumbing to her underlying disease.[24 ]
Woman in Russia[edit]
In 2010, Macchiarini implanted a donated trachea in a woman in Russia while working with surgeon Vladimir Parshin.
Andemariam Teklesenbet Beyene[edit]
Andemariam Teklesenbet Beyene was a man from Eritrea who was studying for a master’s degree in Iceland when he was diagnosed with cancer; The cancer was treated with chemotherapy and surgery in 2009, but in 2011 his trachea became obstructed again. Beyene’s doctors recommended palliative care but also turned to Macchiarini, who was with KI at the time.[27]: 8 In this case, Macchiarini worked with scientists at University College London to create a fully synthetic trachea into which an artificial scaffold was placed B. was treated with Beyene’s marrow cells instead of using a donated and removed trachea as before.[24] The operation took place in June 2011 and received extensive media coverage, including a cover story in The New York Times.[28] At the end of the year, the implant failed, and while Beyene was able to complete his PhD in 2012, he died in January 2013 despite undergoing many treatments at KI.[27]:8 The autopsy showed that Beyene had a chronic lung infection, a clot in his lungs and the artificial trachea had come loose.[27]: 8
Christopher Lyles[edit]
Christopher Lyles lived in the United States; He had tracheal cancer, which was treated with radiation and surgery. He heard about Beyene’s treatment and, through his doctor, asked Macchiarini to do the same for him. Macchiarini undertook, created a fully synthetic trachea seeded with Lyles’ stem cells and implanted it at KI in November 2011.[27]: 9 Lyles died suddenly in 2012 after returning home; no autopsy was performed.[27]:9[29]
Julia Tuulik[ edit ]
In June 2012, Macchiarini Yulia Tuulik implanted a fully synthetic inoculated trachea at the Kuban State Medical University; Tuulik had a tracheostomy as a result of a car accident, but her life was not in danger.[12][30] The graft included a cricoid cartilage, a part of the larynx that Macchiarini had not tried before. The trachea later collapsed and was replaced; she died in 2014.[12] A Russian government investigation later revealed that Macchiarini had operated without a Russian medical license.[12]
Alexander Zozulya[ edit ]
Also in June 2012, Macchiarini Alexander Zozulya, who also had a tracheostomy due to a car accident and whose life was not in danger, implanted a second synthetic-seeded trachea.[12][24][30] The effects of the first implant in 2012 prompted a second surgery in November 2013. Zozulya died in unclear circumstances in February 2014.[24]
Yesim Cetir[ edit ]
Turkish citizen Yesim Cetir underwent routine surgery in 2011 for excessive sweating of her hands, but a mistake severely injured her trachea and damaged her left lung.[24][27]: 9 She came to Macchiarini at KI for treatment, and im In 2012, he first removed her left lung and replaced her trachea with a tube, then replaced the tube with a fully synthetic vaccinated trachea.[27] :9 The next year the implant collapsed and Macchiarini replaced it with a second one.[27] :9 Cetir had many complications from this procedure, constantly having to open her airway and suffering kidney failure.[27] :9 In 2016 she underwent several organ transplants in the US and her trachea was replaced with one from a cadaver.[27] : 9 Cetir died in March 2017.[31]
Hannah Warren[edit]
In April 2013, Macchiarini implanted a fully synthetic trachea in two-year-old Hannah Warren, who was born without one. The operation was performed at OSF Saint Francis Medical Center in Peoria, Illinois, USA.[32] The operation also affected her esophagus, which did not heal properly and required a second operation in June; She died on July 6, 2013 as a result of the second operation.[33]
Sadiq Canaan[ edit ]
In August 2013, Sadiq Kanaan received a fully synthetic tracheal implant from Macchiarini at Kuban State Medical University.[11][24] He died later that same year.[11]
Dmitry Onogda[ edit ]
In June 2014, Macchiarini implanted a fully synthetic trachea in Dmitry Onogda at the Kuban State Medical University. The implant failed and was replaced, and as of 2017 Onogda was still alive.[11][24]
allegations [edit]
Patient blackmail of the University Hospital Careggi
In 2012, Macchiarini was arrested in Italy and charged with asking money from patients at the AOUC to speed up their procedures;[34] the charges were dismissed in May 2015[35] and the prosecutor’s appeal was dismissed in September 2015. [36]
Research misconduct[edit]
In 2014, Macchiarini was accused by four former colleagues and co-authors of making false claims in his research involving AI.[37] The following April, KI’s Ethics Committee issued a response to a series of allegations regarding research ethics and peer review in The Lancet, finding them unfounded.[38]
KI had also hired an outside expert, Bengt Gerdin, to review the allegations and compare the reported findings with the hospital’s medical record; the report was published by the university in May 2015.[39][40][41] Gerdin found that Macchiarini had committed research misconduct in seven articles by failing to obtain ethical approval for some of his surgeries and misrepresenting the outcome of some of those surgeries as well as the work he had performed on animals. 42]
In August 2015, after reviewing the results and receiving a rebuttal from Macchiarini, AI Vice-Chancellor Anders Hamsten found that he had acted “imprudently” but had committed no wrongdoing.[43][44] The Lancet, which published Macchiarini’s work, also published an article defending him.[45]
On January 13, 2016, in an interview with Sveriges Television (SVT), Gerdin criticized the Vice Chancellor’s rejection of the allegations.[46] Later that day, the SVT investigative program document inifrån began airing a three-part series entitled “Experiments” examining Macchiarini’s work.[47][48] The documentary shows Macchiarini continuing to operate with his new transplant method even after it showed little or no promise, and in articles exaggerates the health of his patients as they died. While Macchiarini admitted that the synthetic trachea didn’t work in its current state, he disagreed that trying it on several additional patients without further testing was inappropriate. It was also claimed that the medical condition of the patients, both before and after the operations, as described in scientific papers, did not correspond to reality. Macchiarini also stated that the synthetic trachea had been tested on animals before being used on humans, which could not be verified.[10][18][24]
On January 28, KI issued a statement saying the documentary was making claims it was unaware of and that it would consider reopening its investigation.[49][50] These concerns were echoed by AI chair Lars Leijonborg and Swedish Medical Association chair Heidi Stensmyren, who called for an independent inquiry that would also look at how the problem was being handled by university and hospital leaders.[51]
In February 2016, KI published a review of Macchiarini’s CV that identified discrepancies.[17] The university announced that it would not renew Macchiarini’s research contract, which would expire in November, and the next month Karolinska canceled the contract.[10]
In October 2016, the BBC aired a three-part Storyville documentary entitled Fatal Experiments: The Downfall of a Supersurgeon, directed by Bosse Lindquist and based on the previous Swedish programs on Macchiarini.[52] After the special aired, KI asked Sweden’s national scientific review board to review six of Macchiarini’s papers on the procedures. The panel released its findings in October 2017 and concluded that all six were the result of scientific misconduct, particularly because the complications and deaths that occurred following the procedures were not reported; One of the articles also claimed that the procedure had been approved by an ethics committee, although that was not the case. The board requested that all six papers be withdrawn. It was also said that all of the co-authors had also committed scientific misconduct.[15]
withdrawals [ edit ]
The following papers authored by Macchiarini have been withdrawn:
Other Misconduct[edit]
A story published by Vanity Fair on January 5, 2016 discussed Macchiarini’s affair with a journalist who had written enthusiastic articles about him. The story also challenged statements he had made on his resume.[47][6] The article characterizes him as a serial fable writer and “the extreme form of a fraud” and notes that “the fact that he could keep all the details clear and compartmentalize these different lives and lies is truly amazing.”[6] The article describes one Advertisements and alleged later marriage arrangements from the perspective of an NBC news producer, Benita Alexander. Alexander had been hired by NBC News to produce a 2013 documentary program for Dateline called “A Leap of Faith” to portray Macchiarini, and she ended up having an affair with her subject, only to find out later in 2015 that He was married for thirty years, including the entire courtship period. Details recounted in the article include Alexander telling Macchiarini’s alleged lies about being a surgeon to the stars and current and former heads of state, and a planned marriage to Alexander as the social event of the year (with Pope Francis officiating , Andrea Bocelli singing). , catering of the Enoteca Pinchiorri and numerous celebrities present) reported, among other things, about fake details on his CV. and personal life.[6]
Macchiarini reportedly claimed Pope Francis gave his personal blessing to the marriage between the couple, who are both said to be divorced, and would host the ceremony. The Pope’s spokesman said the Pope did not have a “personal doctor” named Macchiarini, did not know anyone by that name, and had not officiated.[60]
In August 2021, the third season of the Dr. Death podcasts with the release of episodes consisting of a six-episode season about Macchiarini entitled “Miracle Man”. The audio series includes allegations of ethical misconduct and manipulation in Macchiarini’s medical work alongside those of his personal deception in his affair with Alexander, narrated through a series of interviews with the latter.[61]
Fallout for Karolinska Institute [ edit ]
The secretary of the Nobel Committee on Physiology or Medicine, Urban Lendahl, resigned in February 2016 due to his involvement in recruiting Macchiarini to the Karolinska Institutet in 2010.[8][62] Shortly thereafter, Vice Chancellor Anders Hamsten, who had acquitted Macchiarini of scientific misconduct in 2015, also resigned.[9][63]
In August 2016, a committee chaired by Kjell Asplund, set up in February to investigate the three surgeries Macchiarini performed at Karolinska University Hospital, released its report, which found several ethical shortcomings by the hospital and by Macchiarini. it also noted the pressure that the institute put on the hospital in relation to the appointment to the hospital and the translational research of Macchiarini.
Another report was issued in early September examining the institute’s behavior; it was written by a committee headed by Sten Heckscher. The report found that the Institute showed almost no diligence in hiring Macchiarini, in overseeing his work, or in reviewing his performance in reviewing his contracts; The committee found that interference from higher management levels had interfered with the processes.[64][65][66]
On September 5, 2016, the Swedish government applied to dismiss the entire board of the institute.[67] Shortly thereafter, Harriet Wallberg and Anders Hamsten were removed from the jury responsible for the annual selection of the Nobel Prize in Medicine, the selection of which is additionally overseen by the Karolinska Institutet.[68]
court case[edit]
In June 2016, the Swedish police launched an investigation into whether Macchiarini may have committed involuntary manslaughter.[11][24] In October 2017, prosecutors announced that all criminal charges against Macchiarini had been dropped, even though the medical treatment in four out of five cases pursued in Sweden was found to be “negligent” and criminal liability could not be proven.[69] After a year-long medico-legal investigation, the Attorney General’s Office announced in October 2017 that Macchiarini had acted negligently in four of the five cases investigated due to the use of equipment and procedures that was not proven by evidence, but that a criminal offense could not be proven because the patients under each other given treatment may have died.[13][14]
In 2019, an Italian court sentenced Macchiarini to sixteen months in prison for abuse of office and forgery.[70]
On September 29, 2020, Mikael Bjork, head of the public prosecutor’s office in Sweden, charged an unnamed surgeon with aggravated assault. Swedish news agency TT said the surgeon accused was Dr. Paolo Macchiarini. Björk said he resumed the investigation in December 2018 and received new written evidence and interviewed people in five different countries. Björk said the victims suffered “serious bodily injury and great suffering” from the surgeries performed on them and he “assessed that the three surgeries should therefore be considered grievous bodily harm.”[70] Paolo Macchiarini’s trial ended on May 23, 2022, and he was found guilty of assault but not guilty of assault. He was sentenced to probation on June 16, 2022.[71][72]
See also[edit]
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